Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092662 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRDRD2DRD4ALDH1A1 | |
| SCHEMBL29173755 | 0.89 | KMT2A (0.46) | TSHRALDH1A1BRD4MAPK1MEN1 | |
| SCHEMBL30746804 | 0.89 | KMT2A (0.46) | TSHRALDH1A1BRD4MAPK1MEN1 | |
| SCHEMBL29249841 | 0.86 | KMT2A (0.46) | SMN1; SMN2TSHRALDH1A1BRD4MAPK1 | |
| SCHEMBL31092732 | 0.86 | MAPK1 (0.40) | SMN1; SMN2TSHRALDH1A1BRD4MAPK1 | |
| SCHEMBL29249800 | 0.86 | MAPK1 (0.40) | SMN1; SMN2TSHRALDH1A1BRD4MAPK1 | |
| SCHEMBL31092711 | 0.86 | KMT2A (0.46) | SMN1; SMN2TSHRALDH1A1BRD4MAPK1 | |
| SCHEMBL29249838 | 0.86 | HSD17B2 (0.51) | SMN1; SMN2DRD2DRD4ALDH1A1BRD4 | |
| SCHEMBL31092769 | 0.86 | HSD17B2 (0.51) | SMN1; SMN2DRD2DRD4ALDH1A1BRD4 | |
| SCHEMBL31092696 | 0.84 | HSD17B2 (0.46) | SMN1; SMN2TSHRALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324695-A | Method for selectively preparing quinoline-2-ketone or 3, 4-dihydro-quinoline-2-ketone compound under regulation of photocatalyst | 浙江工业大学 | 2024-07-12 | — | — | CN | disclosed |