Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29835138 | 0.89 | ESR2 (0.53) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL23727405 | 0.89 | ESR2 (0.53) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL25226706 | 0.83 | ESR2 (0.50) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL3872624 | 0.80 | ESR2 (0.52) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL29838642 | 0.80 | ESR2 (0.69) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL25176924 | 0.80 | NR1H2 (0.67) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL20570960 | 0.80 | HDAC1 (0.52) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL30097009 | 0.80 | NR1H2 (0.67) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL13337056 | 0.79 | DPP9 (0.58) | ESR2HDAC1NR1H2DDB1CRBN | |
| SCHEMBL18380098 | 0.79 | ESR2 (0.51) | ESR2HDAC1NR1H2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052596-B | ADAMTS inhibitor, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |