Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.53 |
| ▸ | CDK9 | P50750 | 2/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | CDK19 | Q9BWU1 | 4/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.47 |
| ▸ | MERTK | Q12866 | 3/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537438 | 1.00 | CDK2 (0.53) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29065154 | 0.84 | ALK (0.68) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29250626 | 0.81 | MERTK (0.46) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29537475 | 0.81 | MERTK (0.46) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29508046 | 0.80 | CDK2 (0.46) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29065177 | 0.80 | CDK2 (0.46) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL16513510 | 0.78 | CDK19 (0.68) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29250619 | 0.78 | CDK19 (0.68) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29250805 | 0.78 | CCNT1 (0.51) | CDK2CCNT1CCNE1CDK9CCNE2 | |
| SCHEMBL29250677 | 0.78 | MERTK (0.46) | CDK2CCNT1CCNE1CDK9CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |