Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.61 |
| ▸ | CDK9 | P50750 | 4/20 | 0.61 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 4/20 | 0.55 |
| ▸ | BCR | P11274 | 3/20 | 0.55 |
| ▸ | PRKCA | P17252 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 6/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CDK7 | P50613 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584595 | 1.00 | CDK2 (0.61) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL29250699 | 0.83 | AURKA (0.46) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL29537810 | 0.83 | ALK (0.46) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL29538181 | 0.83 | AURKA (0.46) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL29537921 | 0.82 | ABL1 (0.49) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL16513510 | 0.82 | CDK19 (0.68) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL29250619 | 0.82 | CDK19 (0.68) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL29065154 | 0.82 | ALK (0.68) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL16513359 | 0.79 | CDK2 (0.58) | CDK2CCNT1CDK9CCNE2CCNE1 | |
| SCHEMBL23275710 | 0.76 | PIK3CA (0.63) | CDK2ABL1BCRPRKCAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |