Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655099 | 1.00 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL1652701 | 0.91 | GCK (0.85) | GCKKCNH2 | |
| SCHEMBL1427054 | 0.91 | GCK (0.85) | GCKKCNH2 | |
| SCHEMBL2656000 | 0.89 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL2904507 | 0.89 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL2654081 | 0.89 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL2925531 | 0.89 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL2654832 | 0.88 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL2905595 | 0.87 | GCK (0.77) | GCKKCNH2 | |
| SCHEMBL4420471 | 0.87 | GCK (0.80) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756076-B1 | HETROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2010-08-11 | — | — | EP | disclosed |