Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29253198 | 0.87 | CA1 (0.56) | TRIM24TRIM33ALDH1A1CA4FAHD1 | |
| Cyclohexanone SCHEMBL28245306 | 0.84 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CA4FAHD1 | |
| Water SCHEMBL29253128 | 0.76 | TRIM24 (0.54) | TRIM24TRIM33ALDH1A1LMNA | |
| SCHEMBL150852 | 0.76 | — | — | |
| SCHEMBL2700307 | 0.76 | TRIM24 (0.64) | TRIM24TRIM33ALDH1A1MEN1KMT2A | |
| SCHEMBL8036939 | 0.76 | TRIM24 (0.64) | TRIM24TRIM33ALDH1A1MEN1KMT2A | |
| SCHEMBL7645220 | 0.76 | TRIM24 (0.64) | TRIM24TRIM33ALDH1A1MEN1KMT2A | |
| Phosphoric Acid SCHEMBL29253407 | 0.73 | SLC34A1 (0.39) | TRIM24TRIM33ALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL28991415 | 0.71 | — | — | |
| Charcoal, Activated SCHEMBL11198391 | 0.71 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290820-A | Preparation method and application of solid glass beads | 万华化学（宁波）有限公司 | 2024-07-05 | — | — | CN | disclosed |