Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.57 |
| ▸ | IGF1R | P08069 | 3/20 | 0.56 |
| ▸ | INSR | P06213 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520226 | 0.93 | EGFR (0.58) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL29253697 | 0.92 | ALK (0.68) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL22520118 | 0.90 | ALK (0.71) | EGFRALKIGF1RINSR | |
| SCHEMBL21558123 | 0.89 | EGFR (0.68) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL29253766 | 0.89 | JAK3 (0.56) | EGFR | |
| SCHEMBL29253706 | 0.88 | EGFR (0.71) | EGFRIGF1RKCNH2 | |
| SCHEMBL25449395 | 0.84 | ALK (0.61) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL28649641 | 0.83 | ALK (0.68) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL22497639 | 0.82 | ALK (0.71) | EGFRALKIGF1RINSR | |
| SCHEMBL16780916 | 0.82 | ALK (0.78) | EGFRALKIGF1RINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |