Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6504513 | 0.99 | KDM4E (0.32) | KDM4EALDH1A1MAPTTHRBRAD52 | |
| Hydrochloric Acid SCHEMBL6507163 | 0.95 | KDM4E (0.32) | KDM4EALDH1A1MAPTTHRBRAD52 | |
| SCHEMBL2952358 | 0.87 | GAA (0.33) | RAD52 | |
| Hydrochloric Acid SCHEMBL6495184 | 0.86 | GAA (0.32) | RAD52 | |
| SCHEMBL6633118 | 0.83 | GAA (0.32) | RAD52SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6503862 | 0.82 | GAA (0.31) | RAD52SMN1; SMN2 | |
| SCHEMBL2929791 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6495538 | 0.79 | — | — | |
| SCHEMBL6599862 | 0.77 | FFAR1 (0.34) | KDM4EALDH1A1MAPTTHRBRAD52 | |
| Hydrochloric Acid SCHEMBL6098623 | 0.76 | FFAR1 (0.33) | KDM4EALDH1A1MAPTTHRBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1396486-A1 | Bis-paraphenylendiamine derivatives comprising pyrrolidine groups and their use for the colouration of keratinic fibres | L'OREAL (FR) | 2004-03-10 | — | — | EP | claimed |
| EP-1728500-B1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | OREAL (FR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1728500-A1 | Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye | L'OREAL (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1396486-A1 | Bis-paraphenylendiamine derivatives comprising pyrrolidine groups and their use for the colouration of keratinic fibres | L'OREAL (FR) | 2004-03-10 | — | — | EP | disclosed |