Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255364 | 1.00 | TSHR (0.37) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL29255284 | 0.86 | GAA (0.32) | GAA | |
| SCHEMBL29255288 | 0.86 | GAA (0.32) | GAA | |
| SCHEMBL29255387 | 0.83 | TSHR (0.41) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL29255466 | 0.82 | TSHR (0.40) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL21166073 | 0.77 | TSHR (0.46) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL17777936 | 0.75 | TSHR (0.43) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL2671067 | 0.75 | TSHR (0.43) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL5906668 | 0.75 | TSHR (0.43) | TSHRADORA3GAABAZ2BBAZ2A | |
| SCHEMBL31352188 | 0.73 | TSHR (0.42) | TSHRADORA3GAABAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307564-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-07-09 | — | — | CN | disclosed |