Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256553 | 1.00 | PDE2A (0.51) | PDE2ACYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL16959562 | 0.81 | PDE2A (0.46) | PDE2ACYP1A2CYP2C19KCNH2HTR2A | |
| SCHEMBL29256526 | 0.81 | PDE2A (0.54) | PDE2APNMTSCN9AMEN1KMT2A | |
| SCHEMBL29256527 | 0.81 | PDE2A (0.54) | PDE2APNMTSCN9AMEN1KMT2A | |
| SCHEMBL18932350 | 0.79 | PDE2A (0.54) | PDE2ACYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL1508481 | 0.76 | PDE2A (0.50) | PDE2AJAK2JAK1TYK2KCNH2 | |
| SCHEMBL12735210 | 0.75 | PDE2A (0.50) | PDE2ACYP2C19CYP2D6KCNH2HTR2A | |
| SCHEMBL16829650 | 0.75 | PDE2A (0.50) | PDE2ASCN9AKCNH2HTR2ASLC6A4 | |
| SCHEMBL21572137 | 0.75 | PDE2A (0.54) | PDE2ACYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL16829661 | 0.75 | PDE2A (0.50) | PDE2AJAK2JAK1TYK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340754-B | Compound for treating heart failure and related diseases and application thereof | 源道医药(苏州)有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-118340754-A | Compound for treating heart failure and related diseases and application thereof | 源道医药(苏州)有限公司 | 2024-07-16 | — | — | CN | disclosed |