Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30927519 | 0.91 | SCN10A (0.60) | SCN10A | |
| SCHEMBL21906155 | 0.91 | SCN10A (0.60) | SCN10A | |
| Methyl Benzoate SCHEMBL29256638 | 0.91 | SCN10A (0.54) | SCN10A | |
| SCHEMBL25391058 | 0.86 | SCN10A (0.60) | SCN10A | |
| SCHEMBL31163999 | 0.83 | SCN10A (0.66) | SCN10A | |
| SCHEMBL21906041 | 0.80 | SCN10A (0.59) | SCN10A | |
| SCHEMBL29256619 | 0.79 | SCN10A (0.67) | SCN10A | |
| SCHEMBL31037373 | 0.79 | SCN10A (0.67) | SCN10A | |
| SCHEMBL31037395 | 0.79 | SCN10A (0.53) | SCN10A | |
| SCHEMBL31163995 | 0.79 | SCN10A (0.60) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |