Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 18/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | AKT2 | P31751 | 2/20 | 0.38 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25391058 | 0.86 | SCN10A (0.60) | SCN10A | |
| SCHEMBL29256657 | 0.83 | SCN10A (0.47) | SCN10A | |
| SCHEMBL26615889 | 0.83 | SCN10A (0.47) | SCN10A | |
| SCHEMBL31343740 | 0.83 | SCN10A (0.60) | SCN10A | |
| SCHEMBL31037395 | 0.83 | SCN10A (0.53) | SCN10A | |
| SCHEMBL31037406 | 0.82 | SCN10A (0.45) | SCN10A | |
| SCHEMBL31163991 | 0.82 | SCN10A (0.45) | SCN10A | |
| SCHEMBL21906178 | 0.81 | SCN10A (0.64) | SCN10A | |
| SCHEMBL31345669 | 0.81 | SCN10A (0.44) | SCN10A | |
| SCHEMBL26618095 | 0.81 | SCN10A (0.44) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217344-A1 | NAV1.8 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2024-10-24 | — | — | WO | disclosed |
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |