Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256608 | 1.00 | SCN10A (0.55) | SCN10ATP53P2RX1ALDH1A1HTT | |
| SCHEMBL29256631 | 0.99 | SCN10A (0.54) | SCN10ATP53P2RX1ALDH1A1HTT | |
| SCHEMBL29256576 | 0.90 | PPARG (0.54) | SCN10AP2RX1ALDH1A1HTTKDM4E | |
| SCHEMBL29256581 | 0.89 | SCN10A (0.64) | SCN10A | |
| SCHEMBL29256616 | 0.85 | SCN10A (0.67) | SCN10ATP53P2RX1HTTGRM4 | |
| SCHEMBL29256590 | 0.85 | SCN10A (0.67) | SCN10ATP53P2RX1HTTGRM4 | |
| SCHEMBL31037390 | 0.85 | SCN10A (0.67) | SCN10ATP53P2RX1HTTGRM4 | |
| SCHEMBL31037437 | 0.84 | SCN10A (0.66) | SCN10ATP53P2RX1HTTGRM4 | |
| SCHEMBL29256637 | 0.84 | SCN10A (0.66) | SCN10ATP53P2RX1HTTGRM4 | |
| SCHEMBL23779638 | 0.82 | SCN10A (0.82) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217344-A1 | NAV1.8 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2024-10-24 | — | — | WO | disclosed |
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |