Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877819 | 1.00 | EGFR (0.67) | EGFR | |
| SCHEMBL29877352 | 0.94 | EGFR (0.62) | EGFR | |
| SCHEMBL29257987 | 0.94 | EGFR (0.62) | EGFR | |
| SCHEMBL22950994 | 0.93 | EGFR (0.78) | EGFR | |
| Hydrochloric Acid SCHEMBL29257908 | 0.93 | EGFR (0.68) | EGFR | |
| Hydrochloric Acid SCHEMBL29876958 | 0.93 | EGFR (0.68) | EGFR | |
| SCHEMBL29877027 | 0.90 | EGFR (0.61) | EGFR | |
| SCHEMBL25820666 | 0.89 | EGFR (0.73) | EGFR | |
| SCHEMBL29257979 | 0.89 | EGFR (0.71) | EGFR | |
| SCHEMBL25001621 | 0.89 | EGFR (0.62) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888108-B | Novel EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116888108-A | Novel EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2023-10-13 | — | — | CN | disclosed |