Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499541 | 0.98 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL499274 | 0.98 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL108310 | 0.98 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Bromide SCHEMBL1255400 | 0.98 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11785615 | 0.98 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL499748 | 0.98 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10955287 | 0.98 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL110235 | 0.96 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Hydrochloric Acid SCHEMBL1255439 | 0.95 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Iodide SCHEMBL1255015 | 0.95 | TSHR (0.64) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118104655-A | Disinfectant based on virus blocking agent and application thereof | 康码（上海）生物科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118104655-A | Disinfectant based on virus blocking agent and application thereof | 康码（上海）生物科技有限公司 | 2024-05-31 | — | — | CN | disclosed |