SCHEMBL29258141

SCHEMBL29258141

O=C(NCc1ccncc1)Nc1ccc(S(=O)(=O)NCc2cc(F)cc(F)c2)cc1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379874 0.91 NAMPT (1.00) NAMPT
SCHEMBL20379254 0.91 NAMPT (1.00) NAMPT
SCHEMBL30927203 0.90 NAMPT (1.00) NAMPT
SCHEMBL20379324 0.90 NAMPT (1.00) NAMPT
SCHEMBL29258082 0.88 NAMPT (0.65) NAMPT
SCHEMBL30927213 0.87 NAMPT (0.80) NAMPT
SCHEMBL29258218 0.87 NAMPT (0.80) NAMPT
SCHEMBL29258812 0.87 NAMPT (0.83) NAMPT
SCHEMBL29258172 0.87 NAMPT (0.82) NAMPT
SCHEMBL12335069 0.86 NAMPT (1.00) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN claimed
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN disclosed