SCHEMBL29258306

SCHEMBL29258306

O=C(NCc1ccncc1)Nc1ccc(C(=O)NCc2cc(Cl)cc(Cl)c2)cc1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20379630 0.90 NAMPT (0.88) NAMPT
SCHEMBL20379936 0.90 NAMPT (0.80) NAMPT
SCHEMBL30927247 0.90 NAMPT (0.80) NAMPT
SCHEMBL20379957 0.90 NAMPT (0.80) NAMPT
SCHEMBL29258535 0.88 NAMPT (0.67) NAMPT
SCHEMBL29258379 0.86 NAMPT (0.73) NAMPT
SCHEMBL26101409 0.86 NAMPT (0.81) NAMPT
SCHEMBL20379941 0.86 NAMPT (1.00) NAMPT
SCHEMBL30927238 0.86 NAMPT (0.69) NAMPT
SCHEMBL29258501 0.86 NAMPT (0.69) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN claimed
CN-118108664-A NAMPT agonist and preparation method and application thereof 中国人民解放军海军军医大学 2024-05-31 CN disclosed