Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.76 |
| ▸ | AURKA | O14965 | 8/20 | 0.76 |
| ▸ | MET | P08581 | 8/20 | 0.76 |
| ▸ | TEK | Q02763 | 8/20 | 0.76 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.76 |
| ▸ | LCK | P06239 | 4/20 | 0.69 |
| ▸ | ABL1 | P00519 | 1/20 | 0.69 |
| ▸ | LYN | P07948 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.62 |
| ▸ | BRAF | P15056 | 1/20 | 0.62 |
| ▸ | FLT1 | P17948 | 1/20 | 0.62 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.62 |
| ▸ | FLT4 | P35916 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258970 | 0.87 | KDR (0.85) | KDRAURKAMETTEKAURKB | |
| SCHEMBL2748926 | 0.87 | KDR (1.00) | KDRAURKAMETTEKAURKB | |
| SCHEMBL29258986 | 0.87 | KDR (0.78) | KDRAURKAMETTEKAURKB | |
| SCHEMBL4548819 | 0.86 | KDR (0.86) | KDRAURKAMETTEKAURKB | |
| SCHEMBL31300081 | 0.86 | KDR (0.84) | KDRAURKAMETTEKAURKB | |
| SCHEMBL30555195 | 0.86 | KDR (0.81) | KDRAURKAMETTEKAURKB | |
| SCHEMBL4548817 | 0.86 | KDR (0.85) | KDRAURKAMETTEKAURKB | |
| SCHEMBL29258978 | 0.86 | KDR (0.81) | KDRAURKAMETTEKAURKB | |
| SCHEMBL29259493 | 0.86 | KDR (0.83) | KDRAURKAMETTEKAURKB | |
| SCHEMBL29258984 | 0.85 | KDR (0.86) | KDRAURKAMETTEKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025001997-A1 | QUINOLINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2025-01-02 | — | — | WO | disclosed |
| CN-116751161-A | Quinoline compound, preparation method thereof, pharmaceutical composition and medical application | 中国人民解放军军事科学院军事医学研究院 | 2023-09-15 | — | — | CN | disclosed |