Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.62 |
| ▸ | PDE4A | P27815 | 7/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601064 | 1.00 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4DNR1H4 | |
| SCHEMBL29259815 | 0.92 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28334000 | 0.82 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4DITGB3 | |
| SCHEMBL30601073 | 0.81 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28325708 | 0.81 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28324553 | 0.81 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28325671 | 0.81 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28333735 | 0.80 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30601065 | 0.79 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28324549 | 0.79 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305072-B | Compounds with phosphodiesterase 4D and acid sphingomyelinase inhibitory activity and uses thereof | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |