SCHEMBL29259296

SCHEMBL29259296

Oc1cc2ccccc2cc1S

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.48
CYP1A2 P05177 2/20 0.46
ALOX5 P09917 1/20 0.43
GAA P10253 3/20 0.42
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MITF O75030 1/20 0.42
NCOA1 Q15788 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
ALDH1A1 P00352 4/20 0.41
HPGD P15428 3/20 0.41
KDM4E B2RXH2 3/20 0.41
STAT3 P40763 1/20 0.41
NQO2 P16083 1/20 0.41
DAO P14920 3/20 0.40
NPC1 O15118 1/20 0.40
CA12 O43570 1/20 0.40
GMNN O75496 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17796879 0.95 TRPM4 (0.44) TRPM4CYP1A2ALOX5GAAMAPT
SCHEMBL14113980 0.85 TRPM4 (0.36) TRPM4GAAMAPTTDP1ALDH1A1
SCHEMBL29750056 0.82 TRPM4 (0.57) TRPM4CYP1A2ALOX5GAAMAPT
SCHEMBL29363675 0.82 TRPM4 (0.57) TRPM4CYP1A2ALOX5GAAMAPT
SCHEMBL4526767 0.82 CYP2A6 (0.47) CYP1A2MAPTTDP1MEN1KMT2A
SCHEMBL34467656 0.82 CYP2A6 (0.47) CYP1A2MAPTTDP1MEN1KMT2A
SCHEMBL28653 0.82 TRPM4 (0.57) TRPM4CYP1A2ALOX5GAAMAPT
SCHEMBL4068027 0.79 TRPM4 (0.55) TRPM4CYP1A2ALOX5GAAMAPT
SCHEMBL14890636 0.79 TRPM4 (0.55) TRPM4CYP1A2ALOX5GAAMAPT
Hydrochloric Acid SCHEMBL29155327 0.79 TRPM4 (0.55) TRPM4CYP1A2ALOX5GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163476-B Monodentate phosphine ligand, hydroformylation catalyst, and method for preparing linear aldehyde by hydroformylation of olefin 万华化学集团股份有限公司 2023-09-19 CN claimed
CN-114163476-B Monodentate phosphine ligand, hydroformylation catalyst, and method for preparing linear aldehyde by hydroformylation of olefin 万华化学集团股份有限公司 2023-09-19 CN disclosed