SCHEMBL2925945

SCHEMBL2925945

C=C(C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35001 1.00
SCHEMBL8990232 0.94
Hydrochloric Acid SCHEMBL2719617 0.94
Methyl Alcohol SCHEMBL9418859 0.94
Ammonia Solution, Strong SCHEMBL19332652 0.94
Ethylene SCHEMBL9273239 0.94
SCHEMBL8593374 0.94
Ammonia Solution, Strong SCHEMBL2426351 0.94
Hydrochloric Acid SCHEMBL28594736 0.88
Hydrogen Peroxide SCHEMBL28526372 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094653-B1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS PHARMESTE SRL (IT) 2010-09-01 EP claimed
US-7750049-B2 O-substituted-dibenzyl urea-derivatives as TRPV1 receptor antagonists PHARMESTE S.R.L. (IT) 2010-07-06 US claimed
US-20100105740-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS SERENTRIX, LLC 2010-04-29 US claimed
EP-2094653-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS Pharmeste S.r.l. (IT) 2009-09-02 EP claimed
EP-1939173-A1 O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists Pharmeste S.r.l. (IT) 2008-07-02 EP claimed
WO-2008075150-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS PHARMESTE S.R.L. (IT) 2008-06-26 WO claimed
JP-5302214-B2 2013-10-02 JP disclosed
CN-101563317-B O-substituted-dibenzyl urea-derivatives as trpv1 receptor antagonists PHARMESTE SRL 2012-12-12 CN disclosed
EP-2094653-B1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS PHARMESTE SRL (IT) 2010-09-01 EP disclosed
US-7750049-B2 O-substituted-dibenzyl urea-derivatives as TRPV1 receptor antagonists PHARMESTE S.R.L. (IT) 2010-07-06 US disclosed
US-7750049-B2 O-substituted-dibenzyl urea-derivatives as TRPV1 receptor antagonists PHARMESTE S.R.L. (IT) 2010-07-06 US disclosed
US-20100105740-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS SERENTRIX, LLC 2010-04-29 US disclosed
US-20100105740-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS SERENTRIX, LLC 2010-04-29 US disclosed
CN-101563317-A O-substituted-dibenzyl urea-derivatives as TRPV1 receptor antagonists PHARMESTE SRL (IT) 2009-10-21 CN disclosed
EP-2094653-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS Pharmeste S.r.l. (IT) 2009-09-02 EP disclosed
EP-2094653-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS Pharmeste S.r.l. (IT) 2009-09-02 EP disclosed
EP-1939173-A1 O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists Pharmeste S.r.l. (IT) 2008-07-02 EP disclosed
EP-1939173-A1 O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists Pharmeste S.r.l. (IT) 2008-07-02 EP disclosed
WO-2008075150-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS PHARMESTE S.R.L. (IT) 2008-06-26 WO disclosed
WO-2008075150-A1 O-SUBSTITUTED-DIBENZYL UREA-DERIVATIVES AS TRPV1 RECEPTOR ANTAGONISTS PHARMESTE S.R.L. (IT) 2008-06-26 WO disclosed