Symclosene

Symclosene

SCHEMBL29259504

O=c1[nH]c(=O)[nH]c(=O)[nH]1.O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl

nearest known ligand 0.31

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYMP P19971 2/20 0.31
IDH1 O75874 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Symclosene SCHEMBL21090 0.82
Symclosene SCHEMBL18497245 0.82
Symclosene SCHEMBL28935086 0.78
Symclosene SCHEMBL5923704 0.78 APEX1 (0.30)
Troclosene SCHEMBL11377335 0.77
Symclosene SCHEMBL21858976 0.74
SCHEMBL28606 0.73 TYMP (0.31) TYMPIDH1CSNK2A2CSNK2BCSNK2A1
Troclosene SCHEMBL166386 0.73 APEX1 (0.31)
SCHEMBL9062085 0.73 IDH1 (0.44) TYMPIDH1CSNK2A2CSNK2BCSNK2A1
SCHEMBL30107638 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118059911-A Ammoniation heterogeneous interface regulation and control Co-Mo2Preparation method and application of C@NC diatomic catalyst 合肥飞木生物科技有限公司 2024-05-24 CN disclosed