SCHEMBL29259554

SCHEMBL29259554

c1cc(CSSCc2ccncc2)ccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 1.00
CYP1A2 P05177 4/20 1.00
CYP2D6 P10635 4/20 1.00
CYP2C9 P11712 3/20 1.00
CYP2C19 P33261 3/20 1.00
ALDH1A1 P00352 1/20 1.00
HSD17B10 Q99714 1/20 1.00
LOXL2 Q9Y4K0 2/20 0.50
DDAH1 O94760 1/20 0.48
NOS1 P29475 1/20 0.48
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18893321 0.85 CYP1A2 (0.73) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL9150145 0.82 CYP3A4 (0.70) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
Dibenzyl Disulfide SCHEMBL28232592 0.79 CYP1A2 (0.65) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL13107418 0.79 CYP1A2 (0.64) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL1145276 0.78
SCHEMBL1145278 0.78
SCHEMBL23521159 0.76 CYP1A2 (0.61) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL28902097 0.76 CYP2C19 (0.67) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL19514677 0.76 CYP1A2 (0.61) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL8412649 0.74 CYP3A4 (0.58) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165549-A Preparation method of surface protein modified silica nanoparticles 万华化学集团股份有限公司 2024-06-11 CN claimed
CN-118165549-A Preparation method of surface protein modified silica nanoparticles 万华化学集团股份有限公司 2024-06-11 CN disclosed