Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23571917 | 0.84 | CYP1A2 (0.39) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20190189 | 0.83 | SCN10A (0.41) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20190208 | 0.79 | SCN10A (0.35) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20190206 | 0.79 | SCN10A (0.35) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20189464 | 0.78 | CYP1A2 (0.34) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20189463 | 0.78 | CYP1A2 (0.34) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20189923 | 0.77 | SCN10A (0.40) | SCN10AKCNH2CHRNA7TRPV1CACNA2D1 | |
| SCHEMBL30449578 | 0.77 | SCN10A (0.40) | SCN10AKCNH2CHRNA7TRPV1CACNA2D1 | |
| SCHEMBL20189938 | 0.74 | CYP1A2 (0.38) | CYP1A2SCN10AKCNH2ADORA3CHRNA7 | |
| SCHEMBL20189838 | 0.70 | CYP1A2 (0.35) | CYP1A2SCN10AADORA3CHRNA7MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116763791-A | Compounds and methods of use thereof | 普拉克西斯精密药物股份有限公司 | 2023-09-19 | — | — | CN | disclosed |