SCHEMBL29260231 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CRBN	Q96SW2	19/20	0.60

▸	DDB1	Q16531	18/20	0.60

▸	IKZF3	Q9UKT9	5/20	0.60

▸	TNF	P01375	1/20	0.60

▸	IL1B	P01584	1/20	0.60

▸	TBXA2R	P21731	1/20	0.60

▸	IKZF1	Q13422	1/20	0.60

▸	ALDH1A1	P00352	1/20	0.51

▸	CHRM2	P08172	1/20	0.51

▸	OPRM1	P35372	1/20	0.51

▸	CYP1A2	P05177	1/20	0.51

▸	TSHR	P16473	1/20	0.51

▸	TDP1	Q9NUW8	1/20	0.51

▸	BTK	Q06187	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29259962	0.93	CRBN (0.60)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL30135913	0.90	CRBN (0.58)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL24819465	0.90	CRBN (0.58)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL26814086	0.90	CRBN (0.58)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL29260084	0.90	CRBN (0.58)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL31255447	0.89	CRBN (0.56)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL25446186	0.89	CRBN (0.56)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL24481010	0.89	DDB1 (0.59)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL24834648	0.89	CRBN (0.57)	CRBNDDB1IKZF3TNFIL1B
SCHEMBL29986440	0.89	CRBN (0.57)	CRBNDDB1IKZF3TNFIL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-118076607-A	Novel PLK1 degradation inducing compounds	厄普特拉株式会社	2024-05-24	—	—	CN	disclosed