SCHEMBL29263188

SCHEMBL29263188

[CH]1CCc2ccccc21.[Ti]

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.40
TSHR P16473 1/20 0.39
KDM1A O60341 1/20 0.35
HTR2C P28335 1/20 0.35
MAOA P21397 1/20 0.33
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
CYP19A1 P11511 1/20 0.32
PARP1 P09874 1/20 0.32
CES1 P23141 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
TRPA1 O75762 1/20 0.31
ORAI1 Q96D31 1/20 0.31
ORAI2 Q96SN7 1/20 0.31
ORAI3 Q9BRQ5 1/20 0.31
IDO1 P14902 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2680 0.97
SCHEMBL27356586 0.95
SCHEMBL27698774 0.88 MAOB (0.36) MAOBTSHRKDM1AHTR2CMAOA
Trimethylammonium SCHEMBL27854097 0.88 MAOB (0.41) MAOBTSHRKDM1AHTR2CMAOA
SCHEMBL19630481 0.82 TSHR (0.50) MAOBTSHRKDM1AHTR2CMAOA
SCHEMBL1588014 0.78 CES1 (0.43) MAOBTSHRMAOAPARP1CES1
SCHEMBL29385098 0.72 PARP1 (0.40) MAOBTSHRKDM1AHTR2CCYP11B1
SCHEMBL160705 0.72 PARP1 (0.40) MAOBTSHRKDM1AHTR2CCYP11B1
SCHEMBL20184216 0.72 MAOB (0.39) MAOBTSHRKDM1AHTR2CCYP11B1
SCHEMBL1191864 0.72 TSHR (0.43) TSHRCYP11B1CYP11B2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184712-A Method for interfering with continuous movement of carbon atoms in organic molecules 河南省科学院化学研究所有限公司 2024-06-14 CN disclosed