⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135471 | 1.00 | — | — | |
| SCHEMBL5487213 | 0.97 | — | — | |
| SCHEMBL1454184 | 0.79 | TSHR (0.52) | — | |
| SCHEMBL1454061 | 0.79 | TSHR (0.52) | — | |
| SCHEMBL1454253 | 0.79 | TSHR (0.52) | — | |
| SCHEMBL5142056 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL1454264 | 0.76 | — | — | |
| SCHEMBL8102175 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL387549 | 0.76 | — | — | |
| SCHEMBL6672534 | 0.76 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231170-A2 | VIRUS-, BACTERIA-, AND FUNGI-INTERACTING LAYERED PHYLLOSILICATES AND METHODS OF USE | AMCOL INTERNATIONAL CORPORATION (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009110940-A2 | VIRUS-, BACTERIA-, AND FUNGI-INTERACTING LAYERED PHYLLOSILICATES AND METHODS OF USE | AMCOL INTERNATIONAL CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |
| US-7446143-B2 | Intercalates, exfoliates and concentrates thereof formed with protonated, non-carboxylic swelling agent and nylon intercalants polymerized in-situ via ring-opening polymerization | AMCOL INTERNATIONAL CORP. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20050256244-A1 | Intercalates, exfoliates and concentrates thereof formed with protonated, non-carboxylic swelling agent and nylon intercalants polymerized in-situ via ring-opening polymerization | AMCOL INTERNATIONAL CORPORATION (US) | 2005-11-17 | — | — | US | disclosed |