Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 15/20 | 1.00 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.67 |
| ▸ | TLK2 | Q86UE8 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265016 | 1.00 | NTRK1 (1.00) | NTRK1NTRK3TLK2 | |
| SCHEMBL29264958 | 0.84 | NTRK1 (1.00) | NTRK1NTRK3TLK2 | |
| SCHEMBL29264956 | 0.84 | NTRK1 (1.00) | NTRK1NTRK3TLK2 | |
| SCHEMBL29264986 | 0.82 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL29264991 | 0.82 | NTRK1 (1.00) | NTRK1NTRK3 | |
| SCHEMBL30997326 | 0.80 | NTRK1 (0.76) | NTRK1NTRK3 | |
| SCHEMBL29264977 | 0.80 | NTRK1 (0.76) | NTRK1NTRK3 | |
| SCHEMBL29264982 | 0.80 | NTRK1 (0.76) | NTRK1NTRK3 | |
| SCHEMBL29264971 | 0.80 | NTRK1 (1.00) | NTRK1NTRK3TLK2 | |
| SCHEMBL29264975 | 0.80 | NTRK1 (1.00) | NTRK1NTRK3TLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221652-A | Indol-2-one derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118221652-A | Indol-2-one derivative and preparation method and application thereof | 沈阳药科大学 | 2024-06-21 | — | — | CN | disclosed |