Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277356 | 1.00 | PTGIR (0.41) | PTGIRFABP5FABP7KMT2ACASP3 | |
| SCHEMBL29267380 | 1.00 | PTGIR (0.41) | PTGIRFABP5FABP7KMT2ACASP3 | |
| SCHEMBL30792910 | 1.00 | PTGIR (0.41) | PTGIRFABP5FABP7KMT2ACASP3 | |
| SCHEMBL29854970 | 0.91 | FABP5 (0.41) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL29267375 | 0.91 | FABP5 (0.41) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL25178628 | 0.91 | FABP5 (0.41) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL25182302 | 0.91 | FABP5 (0.41) | FABP5FABP7KMT2ACASP3EPHX2 | |
| SCHEMBL30792872 | 0.89 | PTGIR (0.42) | PTGIRFABP5FABP7KMT2ACASP3 | |
| SCHEMBL31681823 | 0.88 | PTGIR (0.41) | PTGIRFABP5FABP7KMT2ACASP3 | |
| SCHEMBL31688526 | 0.88 | PTGIR (0.41) | PTGIRFABP5FABP7KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279933-A | Cyclic compounds having selective KRAS inhibition relative to HRAS and NRAS | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-114195684-B | Synthesis method of amino protecting group N-substituted chiral amino acid | 马鞍山诺恩特医药科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114195684-A | Synthesis method of amino protecting group N-substituted chiral amino acid | 马鞍山诺恩特医药科技有限公司 | 2022-03-18 | — | — | CN | disclosed |