Methane

Methane

SCHEMBL292683

C.C(OCC1CO1)C1CO1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.65
ALDH1A1 P00352 10/20 0.56
MAPK1 P28482 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.54
TDP1 Q9NUW8 3/20 0.50
TP53 P04637 5/20 0.39
CYP3A4 P08684 2/20 0.39
HIF1A Q16665 2/20 0.39
GLA P06280 1/20 0.37
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
PPARG P37231 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
PKM P14618 1/20 0.34
CHRM2 P08172 1/20 0.32
CHRM5 P08912 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4895623 0.97 TSHR (0.68) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL2933671 0.97
SCHEMBL2933673 0.97
SCHEMBL15245 0.97
SCHEMBL4623846 0.97
SCHEMBL216280 0.93 TSHR (0.65) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
Bromide SCHEMBL10338450 0.93 TSHR (0.65) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL4450781 0.93 TSHR (0.65) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
Water SCHEMBL462214 0.93 TSHR (0.65) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
Water SCHEMBL3652389 0.93 TSHR (0.65) TSHRALDH1A1MAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441847-B2 Bi-functionalized polysiloxane brush copolymers HENKEL AG & CO. KGAA (DE) 2025-10-14 US claimed
EP-3932973-B1 BI-FUNCTIONALIZED POLYSILOXANE BRUSH COPOLYMERS HENKEL AG & CO KGAA (DE) 2025-09-03 EP claimed
WO-2025062839-A1 COMPOUND, EPOXY RESIN, CURABLE COMPOSITION, MATERIAL FOR RECYCLING, CURED ARTICLE, METHOD FOR PRODUCING CURED ARTICLE, METHOD FOR PRODUCING DECOMPOSITION PRODUCT, AND DECOMPOSITION METHOD 株式会社ADEKA 2025-03-27 WO claimed
WO-2024070902-A1 COMPOUND, METHOD FOR PRODUCING SAID COMPOUND, CURABLE MATERIAL, CURABLE COMPOSITION, METHOD FOR PRODUCING CURED ARTICLE, AND CURED ARTICLE 株式会社ADEKA 2024-04-04 WO claimed
US-20230117393-A1 Bi-Functionalized Polysiloxane Brush Copolymers LEIBNIZ-INSTITUT FUR KATALYSE E.V. (DE) 2023-04-20 US claimed
WO-2022002606-A1 BI-FUNCTIONALIZED POLYSILOXANE BRUSH COPOLYMERS HENKEL AG & CO. KGAA (DE) 2022-01-06 WO claimed
EP-3932973-A1 BI-FUNCTIONALIZED POLYSILOXANE BRUSH COPOLYMERS Henkel AG & Co. KGaA (DE) 2022-01-05 EP claimed
CN-112279823-A Method for preparing methyl glycidyl ether from epichlorohydrin by-product 江苏扬农化工集团有限公司 2021-01-29 CN claimed
CN-111303112-A Method for fixing carbon dioxide 南京工业大学 2020-06-19 CN claimed
CN-105462318-A Anticorrosive material WANG ZUWEN 2016-04-06 CN claimed
EP-1290058-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-12 EP claimed
US-6376417-B1 COORDINATION CATALYSTS CHINA PETRO CHEMICAL CORP. (CN) 2002-04-23 US claimed
US-20020045707-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2002-04-18 US claimed
WO-2001088013-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2001-11-22 WO claimed
US-6288248-B1 REACTION OF ALLYL CHLORIDE AND PEROXIDE IN WATER AND METHANOL Solvay (Société Anonyme) (BE) 2001-09-11 US claimed
EP-1083187-A1 CATALYST SYSTEM FOR USE IN ETHYLENE POLYMERIZATION AND COPOLYMERIZATION AND PROCESS FOR PREPARING THE SAME CHINA PETROCHEMICAL CORPORATION (CN) 2001-03-14 EP claimed
US-5922633-A THERMAL LATENT ACID CATALYST CONSISTS OF AN EPOXY COMPOUND, A SULFUR COMPOUND AND LEWIS ACID NOF CORPORATION (JP) 1999-07-13 US claimed
US-5710211-A REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL KURARAY CO., LTD. (JP) 1998-01-20 US claimed
EP-0657485-A1 Crosslinkable copolyethers and their use as polymeric electrolytes HYDRO-QUEBEC (CA) 1995-06-14 EP claimed
US-4469615-A Water treating compositions KOHRYU INDUSTRIAL CO. LTD. (JP) 1984-09-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117393-A1 Bi-Functionalized Polysiloxane Brush Copolymers SIGLEC7, SIGLEC9, PUF60 TSHR 3723/4885ALDH1A1 2652/4885MAPK1 4378/4885
US-12441847-B2 Bi-functionalized polysiloxane brush copolymers SIGLEC7, SIGLEC9, PUF60 TSHR 3723/4885ALDH1A1 2652/4885MAPK1 4378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.