Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903380 | 0.85 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL24970264 | 0.85 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL2366192 | 0.83 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL2417915 | 0.83 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2MAPTNR1H2 | |
| SCHEMBL2366069 | 0.82 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL30903367 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL18837988 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL3171182 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL30903374 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL24971004 | 0.81 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076585-A | Gram negative bacteria efflux pump inhibitors | 国家医疗保健研究所 | 2024-05-24 | — | — | CN | disclosed |