Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270701 | 0.94 | CNR2 (0.32) | — | |
| SCHEMBL29270777 | 0.88 | CLK1 (0.33) | — | |
| SCHEMBL29270805 | 0.88 | CNR2 (0.34) | — | |
| SCHEMBL29270844 | 0.87 | CNR2 (0.32) | — | |
| SCHEMBL29270721 | 0.87 | CNR2 (0.32) | TP53 | |
| SCHEMBL26961978 | 0.83 | POLB (0.34) | — | |
| SCHEMBL29270832 | 0.82 | S1PR1 (0.32) | TP53 | |
| SCHEMBL29270734 | 0.81 | TP53 (0.31) | TP53 | |
| SCHEMBL29270806 | 0.81 | MDM2 (0.32) | TP53 | |
| SCHEMBL29270727 | 0.81 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |