Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26962394 | 0.90 | BDKRB1 (0.36) | BDKRB1P2RX3S1PR1POLBMAPT | |
| SCHEMBL26962129 | 0.87 | TRPC3 (0.34) | BDKRB1S1PR1POLBMAPT | |
| SCHEMBL29796828 | 0.84 | HDAC6 (0.38) | BDKRB1P2RX3POLBMAPT | |
| SCHEMBL26961865 | 0.84 | HDAC6 (0.38) | BDKRB1P2RX3POLBMAPT | |
| SCHEMBL26962114 | 0.81 | BDKRB1 (0.34) | BDKRB1KDM4DP2RX3S1PR1POLB | |
| SCHEMBL29796832 | 0.81 | BDKRB1 (0.35) | BDKRB1P2RX3S1PR1POLBMAPT | |
| SCHEMBL26962155 | 0.81 | BDKRB1 (0.35) | BDKRB1P2RX3S1PR1POLBMAPT | |
| SCHEMBL32670508 | 0.81 | HDAC6 (0.38) | BDKRB1P2RX3S1PR1POLBMAPT | |
| SCHEMBL26962186 | 0.81 | HDAC6 (0.36) | BDKRB1P2RX3POLBMAPT | |
| SCHEMBL26962822 | 0.80 | BDKRB1 (0.36) | BDKRB1P2RX3S1PR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964048-A | Bicyclic tetrahydroazepine derivatives for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2023-10-27 | — | — | CN | disclosed |