Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 20/20 | 0.49 |
| ▸ | BRAF | P15056 | 15/20 | 0.49 |
| ▸ | ARAF | P10398 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 4/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30237169 | 0.92 | RAF1 (0.53) | RAF1BRAFARAFKRASKDR | |
| SCHEMBL29272102 | 0.92 | RAF1 (0.53) | RAF1BRAFARAFKRASKDR | |
| SCHEMBL29272256 | 0.88 | RAF1 (0.57) | RAF1BRAFKDR | |
| SCHEMBL30236582 | 0.88 | RAF1 (0.57) | RAF1BRAFKDR | |
| SCHEMBL29272163 | 0.86 | KDR (0.43) | RAF1BRAFARAFKRASKDR | |
| SCHEMBL30236886 | 0.85 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL29272307 | 0.85 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL29272261 | 0.84 | RAF1 (0.47) | RAF1BRAFARAFKRASKDR | |
| SCHEMBL30236650 | 0.84 | RAF1 (0.47) | RAF1BRAFARAFKRASKDR | |
| SCHEMBL30236859 | 0.83 | RAF1 (0.58) | RAF1BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399210-A1 | 6-AZA-QUINOLINE DERIVATIVES AND RELATED USES | Black Diamond Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023039505-A1 | 6-AZA-QUINOLINE DERIVATIVES AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | disclosed |