SCHEMBL29272754

SCHEMBL29272754

CN1CCN(CCOc2cc(OC3CCOC3)c3c(Nc4c(Cl)ccc5c4OCO5)ncnc3c2)CC1

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 19/20 0.92
KDR P35968 11/20 0.92
EGFR P00533 2/20 0.92
LCK P06239 2/20 0.92
YES1 P07947 2/20 0.92
CSK P41240 2/20 0.92
PKMYT1 Q99640 2/20 0.92
BMPR1B O00238 1/20 0.92
GAK O14976 1/20 0.92
EPHB6 O15197 1/20 0.92
RIPK2 O43353 1/20 0.92
STK10 O94804 1/20 0.92
MAP4K4 O95819 1/20 0.92
ABL1 P00519 1/20 0.92
FYN P06241 1/20 0.92
LYN P07948 1/20 0.92
RET P07949 1/20 0.92
HCK P08631 1/20 0.92
PDGFRB P09619 1/20 0.92
FGR P09769 1/20 0.92

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saracatinib SCHEMBL29487213 0.96 SRC (1.00) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL41547 0.96 SRC (1.00) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL29380648 0.96 SRC (1.00) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL29357263 0.96 SRC (1.00) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL4255230 0.95 SRC (0.99) SRCKDREGFRLCKYES1
SCHEMBL3203253 0.92 SRC (1.00) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL29375375 0.90 SRC (0.89) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL4260310 0.90 SRC (0.89) SRCKDREGFRLCKYES1
Saracatinib SCHEMBL4260314 0.90 SRC (0.89) SRCKDREGFRLCKYES1
SCHEMBL3202847 0.90 SRC (1.00) SRCKDREGFRLCKYES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118318033-A Cell aggregate comprising pituitary hormone-producing cells and method for producing the same 住友制药株式会社 2024-07-09 CN disclosed