Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.68 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956249 | 1.00 | ESR1 (0.68) | ESR1ESR2TRIM58MAP4K4BACE1 | |
| SCHEMBL26462184 | 0.90 | ESR1 (0.68) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29274265 | 0.90 | ESR1 (0.70) | ESR1ESR2BACE1KDM4EALDH1A1 | |
| SCHEMBL30956250 | 0.90 | ESR1 (0.70) | ESR1ESR2BACE1KDM4EALDH1A1 | |
| SCHEMBL29043031 | 0.87 | ESR1 (0.54) | ESR1ESR2TRIM58MAP4K4HPGD | |
| SCHEMBL15131709 | 0.86 | ESR1 (0.81) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL194068 | 0.85 | ESR1 (0.73) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29514776 | 0.85 | ESR1 (0.73) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL13556995 | 0.85 | ESR1 (0.62) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29274261 | 0.84 | ESR1 (0.61) | ESR1ESR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239888-A | Modularized synthesis method and application of acridine compound | 厦门大学 | 2024-06-25 | — | — | CN | disclosed |