SCHEMBL2927488

SCHEMBL2927488

Nc1ccc(N2CCC(n3cc[n+](CCCn4cc[n+](C5CCN(c6ccc(N)cc6)C5)c4)c3)C2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6495609 0.99
Bromide SCHEMBL6495700 0.99
SCHEMBL2956801 0.96
Hydrochloric Acid SCHEMBL6493736 0.95
SCHEMBL2927862 0.88 GAA (0.35)
Hydrochloric Acid SCHEMBL6505708 0.87 GAA (0.34)
Bromide SCHEMBL6495862 0.86 MEN1 (0.35)
SCHEMBL2930250 0.84 GAA (0.34)
Hydrochloric Acid SCHEMBL6496555 0.84 GAA (0.33)
SCHEMBL2928431 0.84 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1396486-A1 Bis-paraphenylendiamine derivatives comprising pyrrolidine groups and their use for the colouration of keratinic fibres L'OREAL (FR) 2004-03-10 EP claimed
EP-1728500-B1 Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye OREAL (FR) 2010-01-27 EP disclosed
EP-1728500-A1 Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye L'OREAL (FR) 2006-12-06 EP disclosed
EP-1396486-A1 Bis-paraphenylendiamine derivatives comprising pyrrolidine groups and their use for the colouration of keratinic fibres L'OREAL (FR) 2004-03-10 EP disclosed