SCHEMBL29276558

SCHEMBL29276558

N#CC(=Cc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)o1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.59
TP53 P04637 6/20 0.59
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
LMNA P02545 3/20 0.53
ALDH1A1 P00352 2/20 0.53
THRB P10828 3/20 0.53
HPGD P15428 2/20 0.53
TDP1 Q9NUW8 3/20 0.52
KDM4E B2RXH2 3/20 0.52
KLK7 P49862 1/20 0.52
POLB P06746 4/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
SLC16A3 O15427 1/20 0.50
SLC16A1 P53985 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
RECQL P46063 1/20 0.47
SIRT5 Q9NXA8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15031231 1.00 MAPT (0.59) MAPTTP53MEN1KMT2ALMNA
SCHEMBL23087185 1.00 MAPT (0.59) MAPTTP53MEN1KMT2ALMNA
SCHEMBL12327833 1.00 MAPT (0.59) MAPTTP53MEN1KMT2ALMNA
SCHEMBL12294105 0.98 MAPT (0.60) MAPTTP53MEN1KMT2ALMNA
SCHEMBL14948625 0.88 MAPT (0.48) MAPTTP53MEN1KMT2ALMNA
SCHEMBL12294133 0.88 MAPT (0.55) MAPTALDH1A1HPGDKDM4ESLC16A3
SCHEMBL13573959 0.85 MAPT (0.57) MAPTTP53MEN1KMT2ALMNA
SCHEMBL2825398 0.82 MAPT (0.73) MAPTTP53MEN1KMT2ALMNA
SCHEMBL2825397 0.82 MAPT (0.73) MAPTTP53MEN1KMT2ALMNA
SCHEMBL14773286 0.81 SLC16A3 (0.49) MAPTALDH1A1HPGDKDM4ESLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324996-A Composition for gel electrolyte, electrochromic device and preparation method of electrochromic device 比亚迪股份有限公司 2024-07-12 CN disclosed