Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593783 | 0.81 | MAPT (0.68) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL19268474 | 0.81 | MAPT (0.68) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL712713 | 0.80 | MAPT (0.70) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2822506 | 0.79 | HSD17B10 (0.40) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3611556 | 0.78 | MAPT (0.97) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL712415 | 0.78 | MAPT (0.73) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL950986 | 0.78 | MAPT (0.67) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL165409 | 0.77 | MEN1 (0.69) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4500305 | 0.77 | MAPT (1.00) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1979091 | 0.76 | MAPT (0.65) | LMNAMAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451961-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 广州科恩泰生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2023236960-A1 | CARBOXAMIDE DERIVATIVE HAVING RSK INHIBITORY EFFECT, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 上海科恩泰生物医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-117186098-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 上海科恩泰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |