Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27119032 | 0.88 | CRBN (0.68) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL27119024 | 0.80 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30158164 | 0.78 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL25240043 | 0.78 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL25939703 | 0.78 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30706220 | 0.75 | DDB1 (0.65) | CRBNDDB1POLB | |
| SCHEMBL26925285 | 0.75 | DDB1 (0.65) | CRBNDDB1POLB | |
| SCHEMBL25188462 | 0.73 | HSD17B10 (0.48) | CRBNDDB1POLB | |
| SCHEMBL8190472 | 0.72 | CRBN (0.70) | CRBNDDB1POLB | |
| SCHEMBL27362710 | 0.72 | CRBN (0.57) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232114-B | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |