Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 18/20 | 1.00 |
| ▸ | AURKA | O14965 | 2/20 | 0.68 |
| ▸ | CDK4 | P11802 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16571029 | 0.89 | FGFR4 (0.80) | FGFR4AURKACDK4 | |
| SCHEMBL29277172 | 0.86 | FGFR4 (1.00) | FGFR4AURKACDK4 | |
| SCHEMBL29277203 | 0.85 | FGFR4 (0.74) | FGFR4AURKACDK4 | |
| SCHEMBL29277225 | 0.85 | FGFR4 (0.81) | FGFR4AURKACDK4 | |
| SCHEMBL29277195 | 0.84 | FGFR4 (0.80) | FGFR4AURKACDK4 | |
| SCHEMBL29277215 | 0.83 | FGFR4 (1.00) | FGFR4AURKACDK4 | |
| SCHEMBL29277226 | 0.83 | FGFR4 (0.79) | FGFR4AURKACDK4 | |
| SCHEMBL29277180 | 0.82 | FGFR4 (0.82) | FGFR4AURKACDK4 | |
| SCHEMBL29277231 | 0.81 | FGFR4 (0.72) | FGFR4 | |
| SCHEMBL29277161 | 0.81 | FGFR4 (1.00) | FGFR4AURKACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263940-A | FGFR inhibitor, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2023-12-22 | — | — | CN | claimed |