Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439585 | 1.00 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL29279227 | 1.00 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL26791478 | 1.00 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL1841553 | 1.00 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL1439790 | 1.00 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL1439647 | 1.00 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL1439525 | 0.88 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL1439523 | 0.88 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 | |
| SCHEMBL12812125 | 0.87 | BTK (0.37) | HSD17B10SMN1; SMN2NR1H2BTKPOLB | |
| SCHEMBL27157979 | 0.87 | SMN1; SMN2 (0.44) | HSD17B10SMN1; SMN2NR1H2BTKCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597120-A | Spiroindolone compounds as Kv1.3 potassium Shaker channel blockers | D·E·萧尔研究有限责任公司 | 2024-02-23 | — | — | CN | disclosed |