Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20067445 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL23352264 | 0.91 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL29540787 | 0.91 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| Lysophosphatidylcholine SCHEMBL19787878 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL11131776 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL31577414 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL9560238 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL25336885 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL19065066 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B | |
| SCHEMBL9015289 | 0.90 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1MAPTPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |