SCHEMBL2928021

SCHEMBL2928021

CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)Nc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
KMT2A Q03164 1/20 0.53
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
MAPT P10636 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MMP1 P03956 1/20 0.46
MMP3 P08254 1/20 0.46
MMP9 P14780 1/20 0.46
ANPEP P15144 1/20 0.46
LTA4H P09960 2/20 0.46
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
SIRT5 Q9NXA8 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4599951 0.86 TDP1 (0.52) MEN1GAAKMT2ACA1CA2
SCHEMBL4599955 0.86 TDP1 (0.52) MEN1GAAKMT2ACA1CA2
SCHEMBL8260490 0.85 CA1 (0.51) MEN1GAAKMT2ACA1CA2
SCHEMBL12214968 0.85 CA1 (0.51) MEN1GAAKMT2ACA1CA2
SCHEMBL6287916 0.85 CA1 (0.48) MEN1GAAKMT2ACA1CA2
SCHEMBL6287020 0.85 CA1 (0.48) MEN1GAAKMT2ACA1CA2
SCHEMBL17592256 0.85 CA1 (0.48) MEN1GAAKMT2ACA1CA2
SCHEMBL2931394 0.84 MEN1 (0.52) MEN1GAAKMT2ACA1CA2
SCHEMBL18758851 0.84 CA1 (0.57) MEN1GAAKMT2ACA1CA2
SCHEMBL20067638 0.84 SPHK1 (0.49) MEN1GAAKMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675824-B1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS WURSTER SIEGFRIED (FI) 2010-09-29 EP disclosed
US-7741362-B2 Somatostatin receptor 1 and/or 4 selective agonists and antagonists SIEGFRIED WURSTER (FI) 2010-06-22 US disclosed
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US disclosed
US-20070129422-A1 Somatostatin receptor 1 and/or 4 selective agonists and antagonists OY JUVANTIA PHARMA LTD (FI) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129422-A1 Somatostatin receptor 1 and/or 4 selective agonists and antagonists SSTR4, SSTR1, SSTR3 MEN1 822/4885GAA 2847/4885KMT2A 2112/4885
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 MEN1 822/4885GAA 2847/4885KMT2A 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.