Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.66 |
| ▸ | PDE4A | P27815 | 12/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.66 |
| ▸ | PDE3B | Q13370 | 11/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.65 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24951523 | 0.88 | PDE10A (0.76) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL24954196 | 0.88 | PDE10A (0.68) | PDE10APDE4APDE4BPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL30202096 | 0.87 | PDE10A (0.75) | PDE10APDE4APDE4BPDE3BPDE3A | |
| Ammonia Solution, Strong SCHEMBL29280452 | 0.87 | PDE10A (0.75) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL30201628 | 0.86 | PDE10A (0.66) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL24951313 | 0.86 | PDE10A (0.66) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL24950823 | 0.83 | PDE10A (0.69) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL31106976 | 0.83 | PDE10A (0.69) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL30123364 | 0.82 | PDE10A (0.77) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL3271589 | 0.82 | PDE10A (0.77) | PDE10APDE4APDE4BPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | claimed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | claimed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | claimed |
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |