SCHEMBL29280560

SCHEMBL29280560

CCCN(CCCNC(=O)O)C(=O)C1=Cc2ccc(C(=O)N3CCCC3)cc2N=C(N)C1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 20/20 0.82
TLR7 Q9NYK1 15/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19642416 0.91 TLR8 (1.00) TLR8TLR7
SCHEMBL24699311 0.89 TLR8 (0.75) TLR8TLR7
SCHEMBL24699313 0.89 TLR8 (0.89) TLR8TLR7
Motolimod SCHEMBL29353690 0.85 TLR8 (1.00) TLR8TLR7
Motolimod SCHEMBL254984 0.85 TLR8 (1.00) TLR8TLR7
SCHEMBL29280541 0.85 TLR8 (0.82) TLR8TLR7
SCHEMBL1238499 0.85 TLR8 (0.92) TLR8TLR7
SCHEMBL26080080 0.85 TLR8 (0.95) TLR8TLR7
SCHEMBL1803349 0.85 TLR8 (0.98) TLR8TLR7
SCHEMBL29280545 0.84 TLR8 (0.85) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117769439-A 2-amino-4-carboxamide-benzazepine immunoconjugates and uses thereof 博尔特生物治疗药物有限公司 2024-03-26 CN disclosed