Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29280660 | 0.95 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL3465056 | 0.84 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL6154030 | 0.84 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL11451182 | 0.83 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL6153998 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL28341767 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL9830287 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| Hydrochloric Acid SCHEMBL27854881 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL6153995 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2BACE1GAA | |
| SCHEMBL7561649 | 0.81 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2BACE1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117776997-A | Preparation method of nitrogen-protected 3-hydroxy azetidine | 风火轮(上海)生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117776997-A | Preparation method of nitrogen-protected 3-hydroxy azetidine | 风火轮(上海)生物科技有限公司 | 2024-03-29 | — | — | CN | disclosed |