Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 3/20 | 0.40 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281017 | 0.96 | EDNRA (0.43) | EDNRAAGTR1EDNRBTAS2R8CCNT1 | |
| SCHEMBL30296137 | 0.88 | EDNRA (0.46) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL29280981 | 0.85 | EDNRA (0.44) | EDNRAAGTR1EDNRBTAS2R8CCNT1 | |
| SCHEMBL30296083 | 0.84 | EDNRA (0.47) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL29281011 | 0.83 | EDNRA (0.44) | EDNRAAGTR1EDNRB | |
| SCHEMBL29280988 | 0.81 | EDNRA (0.36) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL30296251 | 0.78 | CARM1 (0.38) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL29281018 | 0.77 | EDNRA (0.37) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL30296158 | 0.74 | EDNRA (0.47) | EDNRAAGTR1EDNRB | |
| SCHEMBL30296109 | 0.74 | EDNRA (0.48) | EDNRAAGTR1EDNRBCCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |