Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104897 | 0.75 | GAA (0.50) | GAAKDM5B | |
| SCHEMBL11295038 | 0.73 | GAA (0.35) | GAA | |
| SCHEMBL18057555 | 0.71 | GAA (0.34) | GAA | |
| SCHEMBL5156756 | 0.69 | — | — | |
| SCHEMBL1030891 | 0.69 | — | — | |
| SCHEMBL15912370 | 0.68 | GAA (0.32) | GAA | |
| SCHEMBL19418897 | 0.68 | NPSR1 (0.34) | GAA | |
| SCHEMBL3175475 | 0.67 | GRIA1 (0.38) | MAP4K4 | |
| SCHEMBL24191100 | 0.67 | BRD4 (0.39) | GAA | |
| SCHEMBL21406490 | 0.67 | GAA (0.47) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |