Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GPX4 | P36969 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31226280 | 0.79 | MAPT (0.44) | GAAGRIA1GRIA3POLBTSHR | |
| SCHEMBL2676823 | 0.78 | MEN1 (0.41) | MEN1GAAKMT2AGRIA1GRIA3 | |
| SCHEMBL31226160 | 0.76 | NPSR1 (0.45) | MEN1KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL3189125 | 0.75 | TSHR (0.44) | MEN1GAAKMT2AGRIA1GRIA3 | |
| SCHEMBL3170099 | 0.72 | GRIA1 (0.46) | MEN1GAAKMT2AGRIA1GRIA3 | |
| SCHEMBL31301207 | 0.70 | POLB (0.34) | MEN1GAAKMT2AGRIA1GRIA3 | |
| SCHEMBL3179817 | 0.69 | GRIA1 (0.44) | MEN1GAAKMT2AGRIA1GRIA3 | |
| SCHEMBL18742872 | 0.69 | — | — | |
| SCHEMBL3175473 | 0.68 | GRIA1 (0.54) | MEN1GAAKMT2AGRIA1GRIA3 | |
| SCHEMBL15652402 | 0.68 | GRIA1 (0.43) | MEN1GAAKMT2AGRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546134-A | Crystal form containing aromatic ring derivative antagonist, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |